Description
About Wysolone 5 mg
Wysolone 5 mg is a prescription dispersible tablet containing 5 mg of prednisolone, made by Pfizer in India (a brand originally developed by Wyeth), used to relieve inflammation in allergic, respiratory, rheumatic, skin and other steroid-responsive conditions. As a dispersible (DT) tablet it can be mixed into a little water, which helps children and adults who find tablets hard to swallow.
How does Wysolone work?
Prednisolone is a man-made corticosteroid closely related to the body’s own cortisol. It lowers the production of substances that fuel inflammation and allergic reactions, including prostaglandins and leukotrienes, and reins in an overactive immune system. Swollen airways, itchy rashes and inflamed joints then begin to settle.
How to take a dispersible tablet
- Place the tablet in a small amount of water, about one or two tablespoons, in a glass.
- Let it break up for a few seconds, stir, and drink it all right away.
- Add a little more water to the glass, swirl and drink it so no medicine is left behind.
- Take it in the morning with or after food, unless your doctor gives other timing.
The tablet can also be swallowed whole with water. Prednisolone tastes bitter, so a drink of juice or milk afterward can help children.
Wysolone for children
Pediatricians use prednisolone for asthma attacks, nephrotic syndrome, severe allergic reactions and some inflammatory conditions. For an asthma attack a common regimen is 1–2 mg/kg once daily for three to five days, to a maximum of 40 mg; the 5 mg tablet makes weight-based doses easy to measure. Long or repeated courses can slow growth, so doctors use the lowest dose that works and track height. Never give a child steroids prescribed for someone else.
Allergies and emergencies
For severe hay fever, hives or allergic swelling, a doctor may add a short course when antihistamines and nasal sprays are not enough. Steroid tablets are not a rescue medicine for anaphylaxis: throat swelling, wheezing or collapse after an allergen needs epinephrine (epinephrine (adrenaline)) and emergency services immediately.
What are the side effects?
Brief courses may cause hunger, sleep problems, stomach upset, hyperactivity or moodiness in children, and higher blood sugar. Longer use can bring weight gain, a rounded face, acne, thin skin, high blood pressure, weaker bones and, in children, slower growth. Get prompt medical help for fever or signs of infection, severe stomach pain, black stools, marked behavior changes, or vision problems.
Who should not take it?
Do not use Wysolone with a systemic fungal infection or an allergy to prednisolone. Tell the doctor about diabetes, high blood pressure, ulcers, tuberculosis, glaucoma, epilepsy or mental health problems. Children and adults who have not had chickenpox or measles should avoid contact with those infections and seek advice fast if exposed; live vaccines may need to wait. NSAIDs, warfarin, diabetes medicines, diuretics, and seizure drugs such as phenytoin interact with it. Courses longer than three weeks must be reduced gradually, not stopped overnight. In pregnancy and breastfeeding, doctors prescribe it when the benefit justifies it.
Pack sizes and storage
Strips of 15 dispersible tablets, sold in packs of 30, 60 or 90, from $5.00. Keep below 77°F (25°C) in the strip until use, since dispersible tablets absorb moisture.
Frequently asked questions
Is Wysolone the same as Omnacortil?
Both contain prednisolone. Omnacortil 5 mg is the Macleods version; stay with one brand unless your doctor agrees to a change.
Are higher strengths available?
Yes: Wysolone 10 mg and Wysolone 20 mg.
What else helps allergy symptoms long term?
Steroid nasal sprays are often used first; see our guide to allergy nasal sprays.
General information only; always follow the directions on your prescription. Wysolone 5 mg is a prescription medicine for use under medical supervision.



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