Description
Same active ingredient (tretinoin) as Retin-A®, the US brand. Retino A Micro 0.1% is an Indian brand, made and licensed in India.
About Retino A Micro 0.1%
Retino A Micro 0.1% is a prescription gel containing tretinoin 0.1% in a microsphere delivery system, made by Janssen Pharmaceuticals in India, used to treat acne vulgaris. It is the higher of the two Retino A Micro strengths, generally used when acne has not responded enough to 0.04% and the skin has adjusted to a retinoid.
0.04% or 0.1%?
| Feature | Retino A Micro 0.04% | Retino A Micro 0.1% |
|---|---|---|
| Tretinoin | 0.04% | 0.1% |
| Typical user | First retinoid, sensitive or drier skin | Oily skin, established retinoid users |
| Irritation | Lower | Higher, especially early on |
| Tube | 15 g | 15 g |
How does Retino A Micro 0.1% work?
The tretinoin sits inside microscopic porous beads. Once on the skin, the beads gradually release the drug into the upper skin layers and follicles. Tretinoin then normalizes the way follicle-lining cells mature, loosening comedones and preventing new blockages. The slow release is meant to deliver a strong concentration with less of the irritation seen with conventional 0.1% products, although redness and peeling can still occur.
How to use it
- Once daily, in the evening, wash with a mild cleanser and pat the skin dry.
- Apply a thin film, about the size of a pea, to the whole area affected by acne.
- Rub in gently until it disappears; keep it well away from the eyes and lips.
- Wash your hands, and use moisturizer if your skin feels tight.
- Apply sunscreen, SPF 30 or above, every morning.
Combining with other acne treatments
For inflamed acne, doctors frequently add benzoyl peroxide, a topical antibiotic such as clindamycin (for example Clindac A Gel), or an oral antibiotic. A common routine is the benzoyl peroxide or antibiotic in the morning and tretinoin at night. Topical antibiotics should not be used on their own for long periods because bacteria become resistant. Do not add salicylic acid, alpha-hydroxy acids, sulfur or resorcinol products without asking, as layering increases irritation.
What are the side effects?
Redness, peeling, dryness, burning, itching and increased sensitivity to sun are common, particularly during the first two to four weeks. An early worsening of acne may occur. Get medical advice for intense irritation, blistering, or swelling of the face or lips.
Who should not use it?
- People who are pregnant or planning pregnancy; breastfeeding mothers should ask their doctor first.
- Anyone with eczema, sunburn or broken skin on the treatment area.
- Children under 12, unless a specialist advises.
- Anyone allergic to tretinoin or the gel ingredients.
Tell your prescriber about medicines that heighten sun sensitivity, and avoid waxing or chemical peels on treated areas.
Pack sizes
15 g tubes, available as 1, 3 or 6 tubes, from $13. Keep below 77°F (25°C) and out of reach of children.
Frequently asked questions
How long before I see results?
Some improvement often appears by week four, with a proper assessment at around 12 weeks.
Can I go back to the lower strength?
Yes, Retino A Micro 0.04% is available if 0.1% is too irritating.
How does it compare with a standard 0.1% gel?
A Ret Gel 0.1% is a conventional gel of the same strength; see all options in the acne category.
General educational information only. Retino A Micro 0.1% is a prescription medicine; your prescriber should guide its use.
Helpful guides
- Tretinoin for Acne: Strengths, How to Use It and What to ExpectA complete guide to tretinoin for acne: which strength to start with, how to apply it step by step, the purging timeline…


