Description
Same active ingredient (fluticasone/salmeterol) as Advair®, the US brand. Seroflo Inhaler 50 mcg is an Indian brand, made and licensed in India. Compare all Generic Advair (Fluticasone/Salmeterol) options.
About Seroflo Inhaler 50 mcg
Seroflo Inhaler 50 mcg is a prescription metered-dose inhaler containing salmeterol 25 mcg and fluticasone propionate 50 mcg per puff, made by Cipla Limited, used as a regular twice-daily maintenance treatment for asthma. It is the lowest-strength Seroflo aerosol, each canister holds 120 puffs, and it is mainly prescribed for children aged 4 and over and for adults whose asthma is controlled on a low steroid dose. In strength it matches the UK’s Seretide 50 Evohaler; the comparable US inhaler, Advair HFA 45/21, labels the same dose as the amount leaving the mouthpiece.
How does Seroflo Inhaler 50 mcg work?
Each puff delivers two medicines that do different jobs. Fluticasone propionate is a corticosteroid that reduces the swelling, mucus and twitchiness of inflamed airways over days to weeks. Salmeterol is a long-acting beta-2 agonist (LABA) that relaxes the airway muscle for about 12 hours. Used together, they control symptoms better than the steroid alone, and the steroid partner is essential: a LABA must never be used on its own for asthma, which is why salmeterol is prescribed in combination.
Who is this strength for?
- Children 4–11 years: when a low-dose steroid inhaler alone does not control asthma. This age range follows UK and European labeling; in the US, the HFA inhaler is labeled from age 12, and younger children are usually given the dry-powder 100/50 strength.
- Teens and adults: as a step-down once asthma is well controlled on a higher strength, or when a low dose is enough.
- Not for COPD: COPD treatment uses higher strengths and different devices.
How to use Seroflo Inhaler 50 mcg
- Remove the cap and shake the inhaler well. Before first use, or after a week without use, release test sprays into the air as the leaflet directs.
- Breathe out gently, away from the mouthpiece.
- Close your lips around it, press the canister once as you start a slow breath in, and keep inhaling.
- Keep the breath in for a count of about ten before letting it out gently, then wait half a minute before the second puff.
- Rinse your mouth with water and spit it out to lower the risk of thrush.
Children should use a spacer: one puff into the chamber, then five slow breaths through the mouthpiece or mask, repeated for the second puff.
Dose
The usual dose for both children and adults is 2 puffs twice a day, morning and evening, roughly 12 hours apart. Do not exceed 2 puffs twice daily. At this rate one canister lasts 30 days. Seroflo is not a reliever; keep a separate quick-acting inhaler such as Asthalin Inhaler for sudden symptoms.
What are the side effects?
Hoarseness, sore throat, oral thrush, headache, and occasionally tremor, palpitations or muscle cramps. In children on inhaled steroids, growth can slow slightly, so the doctor will check height regularly and keep the dose as low as possible. Rarely, wheeze worsens immediately after a puff; use your reliever and seek help. Get urgent care for facial swelling, chest pain or an irregular heartbeat.
Precautions and interactions
Do not stop suddenly, and do not add a second LABA medicine such as formoterol or a salmeterol-only inhaler. Tell the doctor about heart disease, high blood pressure, diabetes, an overactive thyroid, glaucoma or cataracts, and past tuberculosis. Strong CYP3A4 inhibitors, including ritonavir, cobicistat, ketoconazole, itraconazole and clarithromycin, can greatly raise fluticasone and salmeterol levels. Non-selective beta-blockers can trigger bronchospasm. Inhaled steroid combinations are often continued in pregnancy because uncontrolled asthma carries real risks; discuss this with your doctor.
Pack sizes and storage
Available as 1, 2 or 3 inhalers, from $11. Store below 86°F (30°C), away from frost and direct sun, and never puncture or burn the canister.
Frequently asked questions
What if my asthma is not controlled on this strength?
Your doctor may step up to Seroflo Inhaler 125 mcg.
Is there a capsule version?
Yes. Seroflo Rotacaps 100 mcg are inhaled through a capsule device, one capsule twice daily.
How do inhaler types compare?
Our asthma inhaler guide explains aerosols, dry powders and spacers, and the asthma category lists them all.
General information only. Seroflo Inhaler 50 mcg is a prescription medicine; use it every day as your doctor or asthma nurse has shown you.
Helpful guides
- Seroflo vs Advair: Fluticasone/Salmeterol Inhalers ExplainedSeroflo, Seretide and Advair all contain fluticasone and salmeterol. Match the strengths, compare the devices and learn the dosing and safety rules.
- Types of Asthma Inhalers: Relievers, Preventers and How to Use Them CorrectlyLearn the types of asthma inhalers (relievers, preventers and combination inhalers), how each one works, and step-by-step tips for correct inhaler technique.
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